Levon Ambartsumian studied music in the Moscow Central Music School and then in the Moscow Tchaikovsky Conservatory, where his teachers were Mikhail Garlitsky, Felix Andrievski, Yury Yankelevich, Leonid Kogan and Igor Bezrodny. In 1977 he became the First Prize winner of Zagreb International Violin Competition headed by Henryk Szeryng. Two years later he was a prizewinner of the Montreal International Competition, and, in 1981, he won the All-Union Violin Competition in Riga.
Levon Amartsumian was distinguished as Honored Artist of Armenia in 1988 and Honored Artist of Russia in 1997. Since 1977 Levon performed regularly at major venues throughtout the Soviet Union and Eastern Europe as he was not permitted to accept invitations to travel to the West. He collaborated with conductors and composers such as Valery Gergiev, Vladimir Fedoseev, Maxim Shostakovich, Aram Khachaturian, Alfred Schnittke, and many others.
Since 1988 Levon has performed in the United States, Canada, Italy, France, Germany, Greece, Spain, Brazil, and South Korea. In 1989, Ambartsumian founded the Moscow Chamber Orchestra ARCO, which has since then regularly performed in Russia and abroad and is currently based in Athens, Georgia, the United States. Amabartsumian joined the faculty of the Moscow Tchaikovsky Conservatory in 1978, where he taught for 15 years. He was for two years a Visiting Professor at Indiana University School of Music (Bloomington, Indiana). In 1995, Ambartsumian accepted the position of Franklin Professor of Violin at the University of Georgia School of Music (Athens, Georgia).
Ambartsumian devotes himself to contemporary Russian, Armenian and American Music and has made several important world premiers. He has released numerous CDs with music by Wieniawski, Sarasate, Brahms, Mendelssohn, Tchaikovsky, Vivaldi, Stravinsky, Bartok, Shostakovich, Schnittke, Bronner, Arutiunian and other contemporary composers. As a teacher, Ambartsumian has given master classes in Russia, Armenia, South Korea, Canada, Brazil, and France. His former students hold principal positions with major European orchestras in Germany, France, Portugal, and Denmark, and many have been prizewinners at international violin competitions.